Wednesday, October 14, 2009

Snake Venom May Slow Cancer Growth, Studies Hint

Preliminary research shows a natural compound in some snake venoms may prevent the growth of cancerous tumors, potentially transforming one of nature's deadliest toxins into a curative agent.

"Snakes use venom to alter biological functions, and that's what medicine does too," explained John Perez, director of the Natural Toxins Research Center at Texas A&M University-Kingsville. "This is why venoms have always been of interest to medical researchers."

Today roughly a dozen diagnostic tests and drugs are derived from snake venom, according to Zoltan Takacs, a toxinologist (natural-toxins scientist) and herpetologist based at the Yale University School of Medicine in New Haven, Connecticut.

ACE inhibitors, a class of drugs used to treat high blood pressure and other cardiovascular disorders, were developed from the venom of a Brazilian snake. Scientists anticipate that this is just the beginning.

Of the nearly 3,000 species of snakes in the world, about 650 are venomous. Ten of the most deadly live in Australia, making it a logical base for new experiments.

"We knew Australia could be a rich source of drugs because there are so many venomous creatures here," said Tony Woods, a biologist at the University of South Australia in Adelaide. Woods is co-leader of a project to investigate whether the toxins in venom can be used to destroy blood vessels that feed cancerous tumors.

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